Translational Highlights from The Endocrine Society Journals

摘要

The following abstracts from The Endocrine Society Journals have been selected by the editors as being particularly relevant to readers interested in translational science. and Kevin J. Phillips The majority of cholesterol reduction therapies, such as the statin drugs, work primarily by inducing the expression of he- patic low-density lipoprotein receptors (LDLRs), rendering these therapeutics only partially effective in animals lacking LDLRs. Although thyroid hormones and their synthetic deriv- atives, often referred to as thyromimetics, have been clearly shown to reduce serum cholesterol levels, this action has gen- erally been attributed to their ability to increase expression of.