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Immunoinflammatory mediators in the pathogenesis of diabetes mellitus

机译:糖尿病发病机制中的免疫炎症介质

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Characterized as a metabolic syndrome with multiple consequences for the lives of patients, diabetes mellitus is also classified as a chronic non-communicable disease of great scope in the world. It is a complex disease, with different points of view, including the relation between inflammatory process, obesity and insulin resistance due to the performance of the various immunoinflammatory mediators - called adipokines - on glycemic homeostasis. Recent studies have precisely addressed this aspect for the development of drugs that assist in the protection of pancreatic ? cells from the damages arising from oxidative stress and inflammatory process, in order to control the hyperglycemic picture, which is characteristic of diabetes mellitus .
机译:糖尿病被认为是对患者生命造成多种后果的代谢综合症,在世界范围内也被归类为慢性非传染性疾病。它是一种复杂的疾病,具有不同的观点,包括炎症过程,肥胖与胰岛素抵抗之间的关系,这归因于各种免疫炎症介质(称为脂肪因子)对血糖稳态的影响。最近的研究正好针对这一方面,开发有助于保护胰腺癌的药物。氧化应激和炎性过程引起的细胞损伤,以控制血糖升高,这是糖尿病的特征。

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