Eosinophilic Granulomata in a 4 Year Old Girl – A Rare Condition

摘要

Langerhans’ cell histiocytosis (LCH) is a destructive osseous lesion characterized by eosinophils and histiocytes. Eosinophilic granulomata is a localized and mildest form of LCH. A four year old girl presented with mild pain and mobility of prematurely seen mandibular permanent first molar and primary molars on the right side of mandibular region. The gingiva in the involved area was inflamed. A well-defined radioluceny approximately 2cm in diameter with scooped out effect was seen in panoramic radiograph. Extraction of the involved teeth and surgical curettage of the lesion was done under general anesthesia. Obtained bony tissues were histopathologically examined which revealed histiocytic infiltration, further the condition was confirmed by immunohistochemistry. The child underwent chemotherapy and steroidtherapy and responded good.