Update on Diagnosis and Management of Early Stage Diabetic Kidney Disease

摘要

Diabetes mellitus is the most common cause of end stage kidney disease (ESKD) that needs renal replacement therapy (dialysis or kidney transplantation) to sustain life. There is also increased cardiovascular morbidity and mortality in patients with diabetic kidney disease (DKD). In this review article, the diagnosis and the updated different approaches used in the management of early stage DKD has been focused. Various international/ national guidelines and relevant literatures that were published through January 2001 to January 2019 for the recommendations on the diagnosis and management of DKD were reviewed. The benefits of multifactorial interventions in the management of people with early stage DKD to prevent and slow the progression to ESKD, has been clearly demonstrated. Recent studies reveal that some antidiabetic drugs have renoprotective effect evidenced by reduction in albuminuria and improvement in renal function; therefore, they are currently recommended in the management of DKD.