GC-MS INVESTIGATION OF PHYTOCOMPONENTS PRESENT IN ETHANOLIC EXTRACT OF PLANT ICHNOCARPUS FRUTESCENS (L.) W. T. AITON AERIAL PART

摘要

Ichnocarpus frutescens (Apocynaceae) generally renowned as Kali Sariva in Sanskrit, Krishna Sariva in Hindi which is a large, evergreen, red woody climber, native to India, Java, China, Southeast Asia, Ceylon, Northern Australia and found ascending to an altitude of 4,000 ft. Different tribes of India are used this plant as a substitute of Indian Sarsaparilla (Hemidesmus indicus). It has been used conventionally in various diseases and disorders of human being that is a headache, wound, fever, tongue ulcers, cramps, night blindness, stomach pain, bone fracture, skin infection, diabetes, liver disorders, as alterative, tonic, diuretic and diaphoretic. Pharmacologically plant shows different activities include anti-diabetic, anticarcinoma, antiurolithiatic, antiobesity, analgesic, antipyretic, anti-inflammatory, skeletal muscle relaxant, antitumor, hepatoprotective. The present study was aimed to identify the phytocomponents present in I. frutescens using GC-MS analysis. The aerial plant part was extracted successively by solvents according to their increasing order of polarity using Soxhlet apparatus. The phytocomponents of ethanolic extract was identified by GC-MS investigation and found 19 number of phytocomponents. The major constituents of the extracts were 3-O-Methyl-d-glucose, 3, 4, 6-Tri-O-methyl-d-glucose, 2-O-Methyl- D-mannopyranose, Myo-In-ositol, 4-C-methyl and Myo-In-ositol, 2-C-methyl. This study is the prime characterization of the phytocomponents of plant data that indicates the ethanolic extract has remarkable activities.