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Analysis and Algorithmic Generation of Hepatic Vascular Systems

机译:肝血管系统的分析和算法生成

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A proper geometric model of the vascular systems in the liver is crucial for modeling blood flow, the connection between the organ and the rest of the organism. In vivo imaging does not provide sufficient details, so an algorithmic concept for extending measured vascular tree data is needed such that geometrically realistic structures can be generated. We develop a quantification of similarity in terms of different geometric features. This involves topological Strahler ordering of the vascular trees, statistical testing, and averaging. Invariant features are identified in human clinical in vivo CT scans. Results of the existing “Constrained Constructive Optimization” algorithm are compared to real vascular tree data. To improve bifurcation angles in the algorithmic results, we implement a postprocessing step calibrated to the measured features. This framework is finally applied to generate realistic additional details in a patient-specific hepatic vascular tree data set.
机译:肝脏中血管系统的正确几何模型对于建模血流,器官与生物体其余部分之间的连接至关重要。体内成像没有提供足够的细节,因此需要用于扩展测得的血管树数据的算法概念,以便可以生成几何逼真的结构。我们根据不同的几何特征对相似性进行量化。这涉及血管树的拓扑Strahler排序,统计测试和求平均值。在人类临床体内CT扫描中确定了不变特征。将现有“约束构造优化”算法的结果与实际的血管树数据进行比较。为了改善算法结果中的分叉角,我们实施了针对所测量特征进行校准的后处理步骤。该框架最终应用于在特定于患者的肝血管树数据集中生成实际的其他细节。

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