Study on Aptasensors Modified by Ionic Liquid–Fe₃O₄ Based on Microarray Electrodes for Tetracycline Detection

摘要

Aptasensors modified by ionic liquid (IL)-ferroferric oxide(Fe3O4) based on the microarray electrodeswere developed for the detection of tetracycline. The aptasensor was prepared by dropping ionicliquid-ferroferric oxide mixture on a microarray electrode surface. The mixture exhibited a significantsynergistic effect towards the proposed aptasensor. Ionic liquid and ferroferric oxide as thenanocomposites mediator possess the advantage of good electrical conductivity and fast responsespeed.The electrochemical properties of the modified processes were characterized by electrochemicalimpedance spectroscopy (EIS). Different concentration of tetracyclines were detected with thefabricated aptasensor. Under the optimized conditions, the proposed aptasensor provided high sensitivity and a low detection limit (110 M). In addition, it was successfully used to detect thetetracyclines in a real sample.