The Date rape Drug – Flunitrazepam - Electroanalytical Sensing Using Electrogenerated Chemiluminescence

摘要

The electro-analytical sensing of Flunitrazepam is reported for the first time utilising [Ru(bpy)3] as aElectrochemiluminescent reagent probe without any sample pre-treatment. The methodology is shownto be useful for quantifying low ng/mL Flunitrazepam in buffer. We have successfully demonstratedthe detection of Flunitrazepam over a range of Flunitrazepam concentrations 2000 ng/mL to 50 ng/mL2into a pH 4 buffer. A linear response is observed (ECL emission/mV = 0.0094x+6.3204, R = 0.9937and N = 5) with a detection limit of 39 ng/mL (based on 3-sigma).