Efficacy of G32 in treating Pregnancy Gingivitis – A randomised controlled trial

摘要

Background: Pregnant females are susceptible to oral conditions like gingivitis and pregnancy tumour, which affect both the mother and the developing foetus. Chlorhexidine, conventionally used to treat these conditions, causes side effects on long term use. Ayurvedic medications like G32 have been used for treating gingivitis. Objective: To compare efficacy of G32 with Chlorhexidine in treating pregnancy gingivitis after topical application. Materials and Methods: This was a double blind, randomised controlled trial conducted in a sample of 37 pregnant females, in second trimester, with gingivitis. They were randomly divided into two groups and were allotted Chlorhexidine gel (n=18) or G32 gum-paint (n=19) for local application for one month. Plaque index (Silness and L?e, 1964) and Gingival index (L?e and Silness, 1963) were recorded at baseline and follow-up by a calibrated examiner. Statistical analysis was performed using paired t-test for intragroup comparison of mean plaque and gingival scores, and independent t-test for intergroup comparison of mean percentage reduction in plaque and gingival scores. Results: Both test and control groups showed a significant reduction in plaque and gingivitis. The percentage reductions in plaque and gingivitis were similar among the two groups. Conclusion: G32 is effective in treating pregnancy gingivitis and can be economical alternative to Chlorhexidine, with lesser side effects.