Cytotoxic and Phytotoxic Activities of Reinwardtia trigyna (ROXB.)

摘要

The present study was carried out to check the cytotoxic and phytotoxic activities of the ethanolic extract of leaf of Reinwardtia trigyna. The cytotoxic potential checked through Artemia salina mortality test which showed low cytotoxic effect (30% and 43.33%) at the doses of 10μg/ml, and 100μg/ml, while moderate cytotoxic effect (53.33%) was observed at 1000μg/ml with highest LD_(50), value 4496.29μg/ml as compared to the control having normal saline that shows no mortality. The same extracts showed significant dose dependent phytotoxicity 32.25%, 61.29% and 70.96% inhibition of Lemna minor at the doses of 10, 100 and 1000μg/ml as compared to the positive control "Atrazine sulphate" that shows 100% frond inhibition. The FI_(50) value of plant extract was very low as 58.448 μg/ml. it is concluded from the present work that Reinwardtia trigyna could be used as a natural herbicide and weedicide as it shows a good phytotoxic activity.