Prevalence of peripheral arterial disease (PAD) by means of ABI in asymptomatic type II North Indian diabetics and its correlation with cardiovascular risk markers

摘要

Aims: To evaluate the prevalence of PAD by means of anklebrachialindex (ABI) in T2DM patients-stage I grade 0 category 0(Fontaine's stages & Rutherford categories classification of PAD) inNorth Indian population.Methods: Between winter 2012 and summer 2014, 2778 asymptomatic(no complaints pertaining to PAD) Type II diabetes patientswere enrolled. Blood pressure, BMI, baPWV, HbA1c, Cholesterol,HDL, LDL & triglycerides values were analysed. The ABI wasmeasured with VP-2000/1000-Colin Corporation, HyayashiKomaki, Japan. PAD was considered when ABI measured was<0.9 in either leg.Results: We studied 2778 patients (1681 men and 1097 women;mean age 50.4 7.0 years; mean duration of diabetes 7.8 5.9years). The prevalence of PAD was 14.2% with men having aslightly higher prevalence (14.9%), as compared to women(13.2%). ABI was found to be significantly correlated with age(r = 0.15), duration of diabetes (r = 0.09), PWV (r = 0.13 for leftand r = 0.12 for right) and DBP (r = 0.13). We did not find asignificant correlation between measures of obesity (WHR) andPAD.Conclusion: Using ABI, we found prevelance of PAD in 14.2% of type2 diabetics which is comparable to western population. Risk factorssignificantly associated with PAD were – age, duration of diabetes,PWV and DBP. Considering ABI as a significant future CV riskmarker, routine screening of diabetic population is advisable forfuture CV risk prevention.