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Bilateral synchronous testicular seminoma: A rare presentation of a rare disease

机译:双侧同步睾丸精原细胞瘤:一种罕见疾病的罕见表现

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Objective: To present a case of a bilateral synchronous testicular seminoma in a young male clinical stage IIB. Material and method: A 37 years old man presented a bilateral testicular mass with elevated tumoral markers. Histology of frozen section revealed bilateral seminoma and bilateral radical orchiectomy was performed. Result: Enhanced chest and abdominopelvic staging CT scan revealed a lymphadenopathy of 30 mm within the inter-aortocava nodal chain (stage IIB). Patient received three cycles of BEP. Three months later 18F-FDG PET showed no evidence of hypermetabolic activity and serum tumoral markers were normal. Conclusion: Bilateral testicular germ cell tumors are a rare disease. Management of this tumors is controversial. Bilateral radical orchiectomy is the standard of care, nevertheless, in order to preserve fertility and androgen production, an organsparing surgery can be attempted in selected cases. Although prognosis is good, with overall survival rates similar to patients with unilateral disease, life-long close follow-up may be advocated due to relapse risk.
机译:目的:介绍一例年轻男性IIB期双侧同步睾丸精原细胞瘤的病例。材料和方法:一名37岁的男子双侧睾丸肿块,肿瘤标志物升高。冷冻切片的组织学检查显示双侧精原细胞瘤和双侧根治性睾丸切除术。结果:增强的胸部和腹部盆腔分期CT扫描显示,主动脉间淋巴结内有30 mm的淋巴结肿大(IIB期)。患者接受了三个BEP周期。三个月后,18F-FDG PET没有显示出代谢活跃的迹象,血清肿瘤标志物正常。结论:双侧睾丸生殖细胞肿瘤是一种罕见的疾病。这种肿瘤的治疗是有争议的。然而,双侧根治性睾丸切除术是护理的标准,为了保持生育力和雄激素的产生,在某些情况下可以尝试进行器官保留手术。尽管预后良好,但总体生存率与单侧疾病患者相似,但由于复发风险,可提倡终生密切随访。

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