Chemical oxygen demand(COD) reduction of Aqueous Active Pharmaceutical Ingredient of Isorobide 5-mononitrate waste water streams by Advanced Oxidation-Fenton process based on H2O2/Fe+2 salt

摘要

Active Pharmaceutical Intermediates from waste water streams of API companies are emergingcontaminants in the aquatic environment, because of their adverse effect on aquatic life andhumans. These contaminants are high in COD and difficult to treat biologically. In this study,advanced oxidation processes (AOPs) utilizing H2O2/Fe+2, Fenton reactions were investigated inlab-scale experiments for the COD degradation of different waste water streams of ActivePharmaceutical Intermediates -ISMN (Isosorbide 5- Mononitrate) . The experimental resultsshowed that the Fenton process using H2O2/Fe+2 was the most effective Pre treatment processfor waste water streams before Activated sludge process. With Fenton processes, CODReduction of wastewater can be achieved successfully. It is suggested that Fenton processes areviable techniques for the degradation of Active Pharmaceutical Intermediates- ISMN (Isosorbide5- Mononitrate) waste water stream with relatively low toxicity of the by-products in the effluentwhich can be easily biodegradable in the activated sludge process, and other less degradedstreams with high total dissolved solids can be taken to multiple effect evaporator or Reverseosmosis.