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The roles of miRNAs in human breast cancer and canine mammary tumor

机译:miRNA在人类乳腺癌和犬乳腺肿瘤中的作用

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MicroRNAs have become a hot topic in cancer research nowadays due to their important role not only on cancer development, progression, invasion but also on repression of cancer related genes. With advanced technologies, these microRNAs can easily be detected from biopsy samples and blood for early diagnosis, prognosis and treatment. Due to increasing demand of research in exploring expression profile of microRNAs with respect to different subtypes of breast cancer, this review aimed to provide an update on microRNA database available resources, canine breast cancer models, the role of microRNA as oncomir or oncosupressor, detection of microRNAs and potential of miRNAs for breast cancer treatment.
机译:由于MicroRNA不仅在癌症的发展,进展,侵袭中而且在抑制与癌症相关的基因方面起着重要作用,因此它已成为当今癌症研究中的热门话题。借助先进的技术,可以轻松地从活检样本和血液中检测出这些microRNA,以进行早期诊断,预后和治疗。由于探索关于乳腺癌不同亚型的microRNA表达谱的研究需求不断增加,本综述旨在提供有关microRNA数据库可用资源,犬乳腺癌模型,microRNA作为癌基因或抑癌药的作用,检测乳腺癌的最新信息。 microRNA和miRNA在乳腺癌治疗中的潜力。

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