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Plants: The Future Pharmaceutical Factory

机译:植物:未来制药厂

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The main objective of this study was to identify prospects, advantages and challenges of plant molecular farming. Plant-made pharmaceuticals (PMPs) and plant made vaccines (PMVs) were intended to be used for human consumption. A broad range of plants, including crops, vegetables and fruits have been investigated for their applicability in production of pharmaceuticals over the last two decades. At present, mainly maize, rice, tobacco and safflower are used in open field production. Contained bioreactor-type systems focus on moss, algae and plant organ culture. Expression systems include stable transformation of plant genomes—both nuclear and plastid, which are also used in the generation of genetically modified crops, plant-viruses and transient expressions. Each expression system (production platform) offers different advantages and disadvantages. Production platform choice is perceptive and depends on a broad range of criterion. This study is based on literature reviews, document analysis and internet database browsing.
机译:这项研究的主要目的是确定植物分子农业的前景,优势和挑战。植物性药品(PMP)和植物性疫苗(PMV)旨在用于人类消费。在过去的二十年中,已经对包括作物,蔬菜和水果在内的多种植物在药物生产中的适用性进行了研究。目前,在露天生产中主要使用玉米,水稻,烟草和红花。包含的生物反应器类型系统专注于苔藓,藻类和植物器官培养。表达系统包括植物基因组的稳定转化,包括核和质体,它们也用于转基因作物,植物病毒和瞬时表达的产生。每个表达系统(生产平台)都有不同的优点和缺点。生产平台的选择具有感知性,并取决于广泛的标准。这项研究基于文献综述,文档分析和互联网数据库浏览。

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