Frame-core tube structure system is commonly adopted in high-rise office buildings and landmarks, which will cause a large range of damage and serious loss of life and property once the progressive collapse occurs. To analysis the progressive collapse resistance of a high-rise frame-core tube practical project, numerical simulation analysis based on alternate path method and explicit dynamics theory was conducted to study the dynamic response of the remain structure after removing a key member. In addition, large-scaled tests for the frame-core tube structure under static and dynamic loads were carried out to study the behavior and damage situation of the structure. The numerical simulation and test results proved that progressive collapse would not occur when local damages occurred in the bottom corner column, and the structure still has a good seismic performance under dynamic actions. And the feasibility and reliability of the selected numerical simulation method of progressive collapse analysis is proved according to the test results.
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