Innovative method in Neurotherapy, neurology and psychiatry; Investigation of Transcranial laser stimulation (TLS) on EEG rhythms

摘要

The use of transcranial direct current stimulation (tDCS), and transcranial magnetic stimulation (TMS) in many clinical indications in neurology, and psychiatry is well established. Parallel to these researches other scientific studies have shown clinical effects with strong evidences by the use of local Low Level Laser (LLL) in similar clinical conditions. In this paper, we investigated similarities and differences of these methods. We investigated the efficacy of LLL on electroencephalogram (EEG) in a double-blind sham control study. Forty healthy male volunteers aged between 22 and 34 years were randomly assigned to either experiment or sham group. In the present study, subjects in experiment group were exposed to 10Hz at F3 by a LLL radiation, using 1J, 904nm, 300W, pulsed (pulse width 200nsec), approximate time of exposure is 30 minutes in one session. The EEG was recorded before exposure, 2 minutes exactly after exposure, 30 minutes and 90 minutesafter exposure. In this paper, we report the results of EEG changes exactly after exposure. Results indicate that in many regions of the brain, the theta, and alpha EEG rhythms variations in exposed group changed significant in comparison of sham group in both frontal and central regions (P < 0.05) after exposure. Results suggest that compared to sham exposure; some of Local LLL effects significantly persists approximately 90 minutes after exposure. It seems that by LLL radiation, we can change EEG rhythms, and maybe affect brain activities. More studies are needed for finding a conclusion of laser effects on brain, and its functions.