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Development of an online, patient-centred decision aid for patients with oropharyngeal cancer in the transoral robotic surgery era

机译:在经口机器人手术时代为口咽癌患者开发以患者为中心的在线决策辅助工具

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Background ? Radiotherapy (rt) has been the standard treatment for early oropharyngeal cancer, achieving excellent outcomes, but with significant toxicities. Transoral robotic surgery (tors) has emerged as a promising alternative. A decision aid (da) can help to establish patient treatment preferences. Methods A da was developed and piloted in 40 healthy adult volunteers. Assuming equal oncologic outcomes of the treatments, participants indicated their preference. The treatment trade-off point was then established, and participant perceptions were elicited. Results More than 80% of participants initially selected tors for treatment, regardless of facilitator background. For all participants, the treatment trade-off point changed after an average 15% cure benefit. Treatment toxicities, duration, novelty, and perceptions all influenced treatment selection. All subjects valued the da. Conclusions A da developed for early oropharyngeal cancer treatment holds promise in the era of shared decision making. Assuming equal cure rates, tors was preferred over rt by healthy volunteers.
机译:背景 ?放疗(rt)已成为早期口咽癌的标准治疗方法,取得了优异的疗效,但毒性很大。经口机器人手术(tors)已经成为一种有前途的选择。决策辅助(da)可以帮助确定患者的治疗偏好。方法开发一个da da并在40名健康成人志愿者中进行试点。假设治疗的肿瘤学结果均等,参与者表示愿意。然后建立治疗折衷点,并引起参与者的感知。结果不论主持人的背景如何,超过80%的参与者最初都选择了tors进行治疗。对于所有参与者,在平均15%的治愈率后,治疗的折衷点发生了变化。治疗毒性,持续时间,新颖性和知觉都影响治疗选择。所有受试者都重视da。结论为早期口咽癌治疗开发的da在共同决策时代具有希望。假设治愈率相等,健康​​志愿者更喜欢使用rt而不是rt。

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