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Radiosurgery for movement disorders

机译:运动障碍放射外科

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Stereotactic radiosurgery (SRS) has been proposed as an alternative treatment modality to pharmaceutical administration and deep brain stimulation (DBS) for patients suffering from movement disorders. Advanced neuroimaging is required for the identification of the functional structures and the accurate placement of the SRS lesion within the brain. Atlas-based techniques have also been used to aid delineation of the target during treatment planning. Maximum doses greater than 120 Gy have been suggested for controlling movement disorders. These high delivered doses and the irreversible character of SRS require accurate placement of the created lesions. In this article, achievements in the field of stereotactic radiosurgery, neuroimaging, and radiosurgical dose planning are reviewed, and an overview is provided of the clinical experience obtained to date in the radiosurgical treatment of movement disorders.
机译:立体定向放射外科手术(SRS)已被提议作为药物疗法和运动障碍患者深部脑刺激(DBS)的替代治疗方式。需要先进的神经影像学来鉴定脑内SRS病变的功能结构和准确位置。基于图集的技术也已用于在治疗计划期间帮助标定目标。已经建议最大剂量大于120 Gy来控制运动障碍。这些高剂量和SRS的不可逆性要求精确放置所形成的病变。本文概述了立体定向放射外科,神经影像学和放射外科剂量规划领域的成就,并概述了迄今为止在运动障碍的放射外科治疗中获得的临床经验。

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