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Current Nosology of Treatment Resistant Depression: A Controversy Resistant to Revision

机译:抗抑郁治疗的当前学说:抗修订性争议

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Treatment-Resistant Depression (TRD) represents a source of ongoing clinical and nosological controversy and confusion. While no univocal consensus on its definition and specific correlation with major mood disorders has been reached to date, a progressively greater number of evidences tend to suggest a revision of current clinical nosology. Since a better assessment of TRD should be considered mandatory in order to achieve the most appropriate clinical management, this narrative review aims to briefly present current most accepted definitions of the phenomenon, speculating on its putative bipolar diathesis for some of the cases originally assessed as unipolar depression.
机译:抗治疗性抑郁症(TRD)代表了持续的临床和疾病学争议和困惑。迄今为止,虽然尚未就其定义以及与主要情绪障碍的具体相关性达成明确共识,但越来越多的证据倾向于提示对当前临床分类学的修订。由于为了实现最合适的临床管理,必须对TRD进行更好的评估,因此,本篇叙述性评论旨在简要介绍当前最普遍接受的对该现象的定义,并推测其最初被认为是单极的某些病例的假定双极素质。萧条。

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