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Eosinophilic Lung Disease

机译:嗜酸性肺病

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Eosinophilic lung diseases represent a group of disorders in which lung infiltrates seen on a chest radiograph, may or may not be accompanied by peripheral blood eosinophilia. The causes are varied, and range from drug ingestion, parasite or fungal infection, or else, may be idiopathic. The clinical manifestation of these disorders may be mild or severe, depending on the underlying condition. A full history and examination, along with radiological imaging, bronchoscopy, and serological tests are useful in reaching a diagnosis. Treatment with corticosteroids usually results in a good clinical outcome, if the diagnosis is suspected and made early. Early treatment with high dose corticosteroids may be life saving in some patients, whilst other patients require prolonged and sometimes recurrent courses of corticosteroids, due to the chronic relapsing nature of their condition.
机译:嗜酸性肺疾病代表一组疾病,其中在胸部X光片上可见肺浸润,可能伴有或不伴有外周血嗜酸性粒细胞增多。原因多种多样,包括药物摄入,寄生虫或真菌感染,或者可能是特发性的。这些疾病的临床表现可能是轻度的也可能是严重的,具体取决于基础疾病。完整的病史和检查以及放射影像学,支气管镜检查和血清学检查对诊断很有帮助。如果怀疑诊断并提早作出诊断,那么使用皮质类固醇激素治疗通常会产生良好的临床效果。在某些患者中,大剂量皮质类固醇的早期治疗可能会挽救生命,而其他患者则由于其病情的慢性复发性质而需要长期甚至有时复发性的皮质类固醇治疗。

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