New spectrofluorimetric methods for determination of melatonin in the presence of N -{2-[1-({3-[2-(acetylamino)ethyl]-5-methoxy-1 H -indol-2-yl}methyl)-5-methoxy-1 H -indol-3-yl]- ethyl}acetamide: a contaminant in commercial melatonin preparations

摘要

Background Melatonin (MLT) has many health implications, therefore it is of valuable importance to develop specific analytical methods for determination of MLT in the presence of its main contaminant, N-{2-[1-({3-[2-(acetylamino)ethyl]-5-methoxy-1H-indol-2-yl}methyl)-5-methoxy-1H-indol-3-yl]ethyl}acetamide (10). For development of these analytical methods, compound 10 had to be prepared in an adequate amount.