Burden of Persistent Asthma in Patients Treated With Medium- to High-Dose Inhaled Corticosteroids: Baseline Data From a Phase 2 Clinical Trial of Dupilumab

Jonathan Corren; Mario Castro; Vijay Joish; Vera Mastey; Caroline Amand; Christine Taniou; Robert Evans; Mariana Louis Tisserand; Ariel Teper; Laurent Eckert

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Burden of Persistent Asthma in Patients Treated With Medium- to High-Dose Inhaled Corticosteroids: Baseline Data From a Phase 2 Clinical Trial of Dupilumab

机译：中至高剂量吸入糖皮质激素治疗的患者的持续性哮喘负担：Dupilumab 2期临床试验的基线数据

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《Chest》 |2015年第4期|共页
作者
Jonathan Corren; Mario Castro; Vijay Joish; Vera Mastey; Caroline Amand; Christine Taniou; Robert Evans; Mariana Louis Tisserand; Ariel Teper; Laurent Eckert;
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中图分类呼吸系及胸部疾病;
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1. Dupilumab efficacy and safety in adults with uncontrolled persistent asthma despite use of medium-to-high-dose inhaled corticosteroids plus a long-acting beta(2) agonist: a randomised double-blind placebo-controlled pivotal phase 2b dose-ranging trial [J] . Wenzel Sally, Castro Mario, Corren Jonathan, The Lancet . 2016,第10039期

机译：尽管使用中至高剂量吸入皮质类固醇加长效β（2）激动剂，Dupilumab对不受控制的持续性哮喘的成年人的疗效和安全性：一项随机双盲安慰剂对照枢纽性2b剂量范围试验
2. Dupilumab efficacy and safety in adults with uncontrolled persistent asthma despite use of medium-to-high-dose inhaled corticosteroids plus a long-acting beta(2) agonist: a randomised double-blind placebo-controlled pivotal phase 2b dose-ranging trial [J] . Wenzel Sally, Castro Mario, Corren Jonathan, The Lancet . 2016,第10039期

机译：尽管使用中至高剂量吸入皮质类固醇加长效β（2）激动剂，Dupilumab对不受控制的持续性哮喘的成年人的疗效和安全性：一项随机双盲安慰剂对照枢纽性2b剂量范围试验
3. One-year follow up of asthmatic patients newly initiated on treatment with medium- or high-dose inhaled corticosteroid-long-acting beta(2)-agonist in UK primary care settings [J] . Respiratory medicine . 2020,第期

机译：在英国初级保健环境中新发起的哮喘患者新发起的哮喘患者的一年后跟随哮喘患者进行哮喘患者
4. Expression of surface markers on peripheral CD4<'+>CD25<'high> T cells in patients with atopic asthma: role of inhaled corticosteroid [C] . Cao Shukun, rnXu Jing, rnShi Lei, Journal of Organ Dysfunction: ISRD 2007 Abstract Book . 2007

机译：特应性哮喘患者外周血CD4'+ CD25 <'high> T细胞表面标志物的表达：吸入糖皮质激素的作用
5. Addition of leukotriene receptor antagonists versus long acting beta agonists to inhaled corticosteroid therapy for asthma treatment in older adults: A retrospective data analysis of effectiveness, safety and cost. [D] . Altawalbeh, Shoroq Mahmoud. 2015

机译：在吸入性糖皮质激素治疗中，将白三烯受体拮抗剂与长效β激动剂相比，用于老年人的哮喘治疗：有效性，安全性和成本的回顾性数据分析。
6. Asthma Treatment: 187 Reduction in Asthma Deteriorations in Subjects with Persistent Asthma not Well Controlled on Low- Medium- or High-Dose Inhaled Corticosteroids: A Pooled Analysis From Three Clinical Trials Using Combined Mometasone Furoate/Formoterol [O] . Steven Weinstein, Robert Nathan, Eli Meltzer, 2012

机译：哮喘治疗：在低中或高剂量吸入性糖皮质激素治疗中未得到很好控制的持续性哮喘患者中哮喘恶化程度的降低为187％：使用呋喃酮/富马酸联合莫米松的三项临床试验的汇总分析
7. Reduction in asthma deteriorations in subjects with persistent asthma uncontrolled on low-, medium-, or high-dose inhaled corticosteroids: a pooled analysis from three clinical trials using combined mometasone furoate/formoterol [O] . SF Weinstein, RA Nathan, EO Meltzer, 2011

机译：低，中或高剂量吸入皮质类固醇不受控制的持续性哮喘患者哮喘恶化的减少：使用糠酸莫米松/福莫特罗联合进行的三项临床试验的汇总分析

Burden of Persistent Asthma in Patients Treated With Medium- to High-Dose Inhaled Corticosteroids: Baseline Data From a Phase 2 Clinical Trial of Dupilumab

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