POINT: Does Low-Dose Oxygen Expose Patients With COPD to More Radiation-Like Risks Than Patients Without COPD? Yes

摘要

We argue that low-dose oxygen therapy (LDOT) does expose patients with COPD to more radiation-like risks?than patients without COPD. Three considerations subtend our assertion: radiation and oxygen share oxidative stress mechanisms that constitute radiation-oxygen injury homology (ROIH); patients with COPD have higher, more problematic exposure rates to LDOT vs?patients without COPD; and patients with COPD vs?patients without COPD have disease burdens that amplify ROIH from LDOT. Thus, LDOT, independent of benefits, poses radiation-like risks with pernicious results that follow stochastic patterns.