Catheter-RelatedAcremonium kilienseFungemia in a Patient with Ulcerative Colitis under Treatment with Infliximab

摘要

Acremoniumspp. are filamentous, cosmopolitan fungi commonly isolated from plant debris and soil. They are infrequent pathogens in humans.Acremoniumfungemia has been reported in neutropenic patients associated with central venous catheters and in nonneutropenic patients receiving long-term total parenteral nutrition. TNF-αblockade is associated with fungal infections, but noAcremoniumspp. infection had been reported up to the present. In this paper, we present a patient with ulcerative colitis who developedAcremonium kiliensefungemia associated with infliximab therapy while receiving total parenteral nutrition. The patient was successfully treated with voriconazole.Acremoniumsp. infection must be suspected as another cause of fungal infection in patients under treatment with infliximab.