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Therapeutic effect of an anaplasmicid and ant-protozoa product against the blood parasites of cattle

机译:杀虫剂和原虫产品对牛血液寄生虫的治疗作用

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In Colombia all cattle raising areas located in tropical areas of low and medium altitude are considered endemic for haemoparasites of cattle, but sometimes losses are minimized by the development of immunity and the achievement of a state of equilibrium in populations. Generally, in the field the use of effective drugs is required as a help in the control of clinical manifestations associated with the occurrence of these diseases. This study was aimed to validate the benefit of the use of an anaplasmicid and anti-protozoa product (Ganaplus®) for the control of clinical events associated with blood parasites in cattle. The study consisted of a experimental phase based on artificial inoculation of cattle with Anaplasma marginale, Babesia bigemina and Babesia bovis; and a field phase that evaluated clinical events in animals raised in endemic areas. In both phases, blood sample collection and measurement of body temperature were conducted. Complete hemogram, hematocrit, and blood smears for parasite analysis were performed. Cattle of the experimental phase showed very low parasitemia, with slight changes in hematologic parameters, but the animals that demonstrated clinical acute states successfully responded to the application of the compound, restoring their hematologic parameters. The cattle of the field phase showed higher parasitemias, with clear reductions in the hematocrit and the presence of an acute clinical syndrome, which responded appropriately to the product application. It was confirmed that the compound tested is a good medicine for the treatment of clinical disease associated with blood parasites.
机译:在哥伦比亚,位于低海拔和中海拔热带地区的所有养牛场都被认为是牛血寄生虫的地方病,但有时由于免疫力的提高和种群平衡的实现,损失最小。通常,在该领域中,需要使用有效的药物来帮助控制与这些疾病的发生有关的临床表现。这项研究旨在验证使用类抗虫和原生动物产品(Ganaplus®)来控制与牛血液寄生虫有关的临床事件的益处。这项研究包括一个实验阶段,该阶段基于人工接种牛无性无浆膜,双歧杆菌和牛乳杆菌。还有一个野外阶段,用于评估在流行地区饲养的动物的临床事件。在两个阶段都进行了血液样本采集和体温测量。进行了完整的血图,血细胞比容和血液涂片进行寄生虫分析。实验期的牛显示出极低的寄生虫血症,血液学参数略有变化,但是表现出临床急性状态的动物成功地对该化合物的使用产生了反应,恢复了其血液学参数。田间阶段的牛表现出较高的寄生虫病,血细胞比容明显降低,并出现急性临床综合症,对产品的使用做出了适当的反应。证实了所测试的化合物是治疗与血液寄生虫相关的临床疾病的良好药物。

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