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Laryngeal granuloma in a thorougbread horse: a multidisciplinary study

机译:胸马中的喉肉芽肿:多学科研究

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A two year-old racing thoroughbred mare presented with loud respiratory stertor, that was auscultated in the tracheal and laryngeal regions. Upon palpitation of the larynx, no changes were noted. The upper respiratory tract was examined via a fiberoptic endoscopy where the nasal passages were observed to be unchanged and the scope passed with normal resistance. The guttural pouches and their openings were normal. The right arytenoid cartilage appeared thickened throughout its length and failed to retract during inspiration. In the right, dorsal cricoarytenoid cartilage a gross mass was observed projecting from the right wall. The mass was surgically removed from the larynx and samples were collected for histopathologic and bacterial study. Histopathologic study of the cricoid cartilage revealed extensive proliferation of fibrous connective tissue, well vascularized granulation tissue with diffuse infiltration of lymphocytes, plasma cells and a few giant cells. Bacterial cultures provided isolation of Pseudomonas aeruginosa, whose antibiogram demonstrated sensitivities to ampicillin, ceftazidime, ciprofloxacin, cefepime, gentamicin, imipinem, meropenem, piperacillin, piperacillin/tazobactam and resistance to trimethoprim. In conclusión, a laryngeal granuloma was detected in a racing thoroughbred mare by a multidisciplinary, clinical study involving endoscopy, as well as histopathologic and microbiologic studies.
机译:两岁的赛马纯种母马,呼吸道震颤强烈,在气管和喉部听诊。触诊喉后,未发现任何变化。通过纤维内窥镜检查上呼吸道,其中观察到鼻道未变并且范围以正常阻力通过。咽袋及其开口正常。右侧的软骨样软骨在其整个长度上似乎变厚,并且在吸气过程中未能缩回。在右侧,观察到背环环软骨样软骨的总质量从右侧壁突出。从喉部手术去除肿块,并收集样品用于组织病理学和细菌研究。环状软骨的组织病理学研究显示,纤维结缔组织,血管化良好的肉芽组织广泛扩散,淋巴细胞,浆细胞和少数巨细胞弥散浸润。细菌培养物分离出铜绿假单胞菌,其抗菌素谱显示对氨苄青霉素,头孢他啶,环丙沙星,头孢吡肟,庆大霉素,阿米品碱,美罗培南,哌拉西林,哌拉西林/他唑巴坦敏感,并对甲氧苄啶具有抗药性。结论是,通过一项涉及内窥镜检查的多学科临床研究以及组织病理学和微生物学研究,在一个赛马纯种母马中发现了喉部肉芽肿。

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