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Bovine dermal fibrosarcoma: a case report

机译:牛真皮纤维肉瘤:一例报告

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Fibrosarcomas are tumors of varying frequency in domestic animals, with cats being most affected by them. However, the cases reported in bovines are few and its description is mainly centered on the female reproductive system, at the level of the vagina, where its presentation may be associated to other types of neoplasms. In this report the case of a 4 year old bovine female with a mass located in the left mandibular edge is presented, with an approximate evolution of a month of progressive growth. Through surgical procedure the mass was removed and submitted to the pathology lab of the Universidad de Nariño, with dimensions of 6x9x3cm, skin and hair, regular surface, a whitish color and hard consistency; for processing and routine dying with hematoxylin-eosin stain. The sample was classified as a malignant neoplasm of expansive type derived of spindle cells, therefore differential dying was performed with Masson's trichrome stain for its diagnosis, resulting positive for component collagen fibrosarcoma given the distribution pattern with moderate cellular pleomorphism, nuclear pleomorphism, anisocytosis and low megalocytosis, anisokaryosis and megalokaryosis with 3 mitotic figures in 10 random fields at 400X. Additionally, immunostaining with desmin and vimentin markers was performed to establish the definitive diagnosis, being this the first reported case of this type of neoplasm in the department of Nariño, Colombia.
机译:纤维肉瘤是家畜中不同频率的肿瘤,猫受其影响最大。但是,在牛中报道的病例很少,其描述主要集中在阴道水平的女性生殖系统上,在该系统中其表现可能与其他类型的肿瘤有关。在本报告中,例举了一个4岁的牛雌性,其肿块位于下颌左缘,大约一个月的逐渐增长。通过外科手术将肿块取出并送入纳里尼奥大学病理实验室,其尺寸为6x9x3cm,皮肤和头发,表面规则,发白,颜色坚硬。用于苏木精-曙红染色的处理和常规染色。该样品被归类为纺锤状细胞来源的扩张型恶性肿瘤,因此使用Masson三色染色进行鉴别染色以进行诊断,鉴于分布模式具有中等细胞多态性,核多型性,异胞性和低,因此对胶原纤维肉瘤成分呈阳性在10倍随机区域以400X扫描,具有3个有丝分裂形态的巨细胞增多症,反核和巨核病。此外,还进行了用结蛋白和波形蛋白标记物的免疫染色以建立明确的诊断,这是哥伦比亚纳里尼奥省首次报道的这类肿瘤。

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