Optical coherence tomography: a novel modality for scrotal imaging

摘要

Background For patients with nonobstructive azoospermia, sperm retrieval rates remain modest. We describe the use of optical coherence tomography to improve retrieval rates and to decrease tissue destruction. Methods Four patients underwent diagnostic testicular biopsy and imaging with the Niris optical coherence tomography device. We performed a descriptive comparison between optical coherence tomographic images and conventional histology. Results The measured seminiferous tubule diameter differed by 16 μm between comparative imaging from optical coherence tomography and conventional histology using hematoxylin and eosin staining. Conclusion We illustrate the usefulness of optical coherence tomography in the setting of testicular biopsy and the management of nonobstructive azoospermia.