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Knee arthrodesis versus above-the-knee amputation after septic failure of revision total knee arthroplasty: comparison of functional outcome and complication rates

机译:翻修全膝关节置换术失败后的膝关节置换术与膝上截肢术:功能结局和并发症发生率的比较

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After septic failure of total knee arthroplasty (TKA) and multiple revision operations resulting in impaired function, bone and/or soft-tissue damage a reconstruction with a revision arthroplasty might be impossible. Salvage procedures to regain mobility and quality of life are an above-the-knee amputation or knee arthrodesis. The decision process for the patient and surgeon is difficult and data comparing arthrodesis versus amputation in terms of function and quality of life are scarce. The purpose of this study was to analyse and compare the specific complications, functional outcome and quality of life of above-the-knee amputation (AKA) and modular knee-arthrodesis (MKA) after septic failure of total knee arthroplasty. Eighty-one patients treated with MKA and 32 patients treated with AKA after septic failure of TKA between 2003 and 2012 were included in this cohort study. Demographic data, comorbidities, pathogens and complications such as re-infection, implant-failure or revision surgeries were recorded in 55MKA and 20AKA patients. Functional outcome with use of the Lower-Extremity-Functional-Score (LEFS) and the patients reported general health status (SF-12-questionnaire) was recorded after a mean interval of 55?months. A major complication occurred in more than one-third of the cases after MKA and AKA, whereas recurrence of infection was with 22% after MKA and 35% after AKA the most common complication. Patients with AKA and MKA showed a comparable functional outcome with a mean LEFS score of 37 and 28 respectively (p?=?0.181). Correspondingly, a comparable physical quality of life with a mean physical SF-12 of 36 for AKA patients and a mean score of 30 for MKA patients was observed (p?=?0.080). Notably, ten AKA patients that could be fitted with a microprocessor-controlled-knee-joint demonstrated with a mean LEFS of 56 a significantly better functional outcome than other amputee patients (p?
机译:在全膝关节置换术(TKA)败血症失败和多次翻修手术导致功能受损,骨骼和/或软组织损伤后,采用翻修置换术进行重建可能是不可能的。挽救活动以恢复活动能力和生活质量是膝盖以上截肢或膝关节固定术。对于患者和外科医生而言,决策过程很困难,并且在功能和生活质量方面比较关节固定术与截肢术的数据很少。这项研究的目的是分析和比较全膝关节置换术败血症后膝上截肢术(AKA)和模块化膝关节置换术(MKA)的具体并发症,功能结局和生活质量。该队列研究纳入了2003年至2012年间在TKA败血症后接受MKA治疗的81例患者和接受AKA治疗的32例患者。记录了55MKA和20AKA患者的人口统计学数据,合并症,病原体和并发症,如再次感染,植入物失败或翻修手术。在平均间隔55个月后记录下肢功能评分(LEFS)和报告总体健康状况(SF-12-问卷)的患者的功能结局。 MKA和AKA术后三分之一以上的病例发生了主要并发症,而MKA术后感染的复发率为22%,AKA术后感染的复发率为35%。 AKA和MKA患者表现出可比较的功能结局,平均LEFS评分分别为37和28(p?=?0.181)。相应地,观察到相当的身体生活质量,AKA患者的平均身体SF-12值为36,MKA患者的平均身体得分为30(p = 0.080)。值得注意的是,十名可以安装微处理器控制的膝关节的AKA患者的平均LEFS为56,其功能结果明显优于其他截肢患者(p 0.01)或MKA患者(p 0.01) )。自然地,翻修膝关节置换术后治疗败血症失败状态的决策过程取决于各种因素。但是,对于身体和精神状况良好的患者,应该考虑采用截肢术。

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