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A geometric method for contour extraction of Drosophila embryos

机译:果蝇胚胎轮廓提取的几何方法

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High resolution images of Drosophila embryos in their developmental stages contain rich spatial and temporal information of gene expression. Automatic extraction of the contour of an embryo of interest in an embryonic image is a critical step of a computational system used to discover gene-gene interaction on Drosophila. We propose a geometric method for contour extraction of Drosophila embryos. The key of the proposed geometric method is k-dominant point extraction that is a generalization of 3-dominant point extraction proposed in our previous work. Based on k-dominant point extraction, we can approximate a connected component of edge pixels by a polygon that can be either convex or concave. The test on BDGP data shows that the proposed method outputforms two existing methods designed for contour extraction of Drosophila embryos. The main advantage of the proposed geometric method in the context of contour extraction of Drosophila embryos is its ability of segmenting embryos touching each other. The proposed geometric method can also be applied to applications relevant to contour extraction.
机译:果蝇胚胎在其发展阶段的高分辨率图像包含丰富的基因表达的时空信息。在胚胎图像中自动提取目标胚胎的轮廓是用于发现果蝇上基因与基因相互作用的计算系统的关键步骤。我们提出了一种果蝇胚胎轮廓提取的几何方法。提出的几何方法的关键是k优势点提取,这是我们先前工作中提出的3优势点提取的概括。基于k优势点提取,我们可以通过可以是凸的或凹的多边形来近似边缘像素的连接分量。对BDGP数据的测试表明,该方法输出了两种设计用于果蝇胚胎轮廓提取的现有方法。在果蝇胚胎轮廓提取的背景下,所提出的几何方法的主要优点是能够分割彼此接触的胚胎。所提出的几何方法也可以应用于与轮廓提取有关的应用。

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