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首页> 外文期刊>BMC Gastroenterology >Endoscopic balloon dilatation for benign hepaticojejunostomy anastomotic stricture using short double-balloon enteroscopy in patients with a prior Whipple’s procedure: a retrospective study
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Endoscopic balloon dilatation for benign hepaticojejunostomy anastomotic stricture using short double-balloon enteroscopy in patients with a prior Whipple’s procedure: a retrospective study

机译:内镜下球囊扩张术治疗Whipple早期手术的患者,应用双气囊小肠镜进行良性肝空肠吻合术狭窄的回顾性研究

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Endoscopic retrograde cholangiography using a short double-balloon endoscope (DB-ERC) is a promising minimally-invasive method for accessing hepaticojejunostomy (HJ) anastomosis in patients with surgically altered anatomy. We aimed to evaluate the immediate and long-term outcomes of balloon dilatation for benign HJ anastomotic stricture (HJAS) in patients who had previously undergone Whipple’s procedure using a DB-ERC. We conducted a retrospective analysis of 46 patients who underwent balloon dilatation alone with a DB-ERC for benign HJAS between November 2008 and November 2014. The median follow-up duration was 3.5 (interquartile range [IQR], 1.9–5.1) years. The technical and clinical success rates were 100%, and adverse events occurred in 7% (3/46, cholangitis). The median hospitalization period was seven (IQR, 5–10) days. Of 42 patients (91%) followed-up for >?1?year, 24 (51%) had recurrent HJAS at a median of 1.2 (IQR, 0.6–2.9) years after balloon dilatation. The cumulative anastomotic patency rates at 1, 2, and 3 years were 73, 55, and 49%, respectively. In univariate analysis, early stricture formation (
机译:使用短双气囊内窥镜(DB-ERC)进行内窥镜逆行胆管造影术是一种有前景的微创方法,可用于手术解剖结构改变的患者进行肝空肠吻合术(HJ)吻合。我们的目的是评估先前曾接受过DB-ERC手术的Whipple手术的患者,对于良性HJ吻合口狭窄(HJAS),球囊扩张的近期和长期疗效。我们对2008年11月至2014年11月间接受良性HJAS的DB-ERC单独行球囊扩张术的46例患者进行了回顾性分析。中位随访时间为3.5年(四分位间距[IQR],1.9-5.1)年。技术和临床成功率为100%,不良事件发生率为7%(3/46,胆管炎)。中位住院期为七(IQR,5-10)天。 42例(91%)随访≥1年的患者中,有24例(51%)球囊扩张后HJAS复发的中位数为1.2年(IQR,0.6-2.9)年。在1年,2年和3年时,累计吻合口通畅率分别为73%,55%和49%。在单因素分析中,尽早狭窄(<?1?年)是复发性狭窄的危险因素,尽管在多因素分析中未观察到统计学上显着的危险因素。良性HJAS内镜下球囊扩张术与DB-ERC联合治疗是安全有效的,具有良好的即时技术成功率,且不良事件少。需要对该程序做进一步的改进,以防止HJAS复发。

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