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Evaluation of choroidal parameters in eyes at the first onset of acute anterior uveitis

机译:急性前葡萄膜炎初发时眼中脉络膜参数的评估

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Little is known about choroidal involvement in anterior uveitis. The aim of our study was to evaluate changes in choroidal thickness and volume in eyes with acute anterior uveitis (AAU) using enhanced depth imaging-optical coherence tomography (EDI-OCT) at baseline and after treatment, which were compared with healthy fellow eyes. For the study, 35 individuals with unilateral acute AAU at the first onset were enrolled. Subfoveal thickness and choroidal volume were measured with EDI-OCT in nine Early Treatment of Diabetic Retinopathy Study (ETDRS) subfields before and after the completion of treatment. Moreover, axial length measurements of both eye bulbs were determined by optical biometry. No statistically significant differences in choroidal thickness or choroidal volume were detected between AAU eyes at baseline and after treatment and fellow eyes. Positive correlations between the values of anterior chamber flare and absolute CT changes in both temporal and inferior ETDRS fields, as well as in superior outer ring were detected. Negative correlations between age and both choroidal thickness and choroidal volume were detected in AAU eyes at baseline and after treatment, as well as in fellow eyes. Evaluation of the choroid with EDI-OCT does not appear to be a reliable tool for the treatment monitoring of eyes with anterior uveitis.
机译:关于脉络膜受累于前葡萄膜炎知之甚少。我们研究的目的是在基线和治疗后使用增强的深度成像光学相干断层扫描(EDI-OCT)评估急性前葡萄膜炎(AAU)眼中脉络膜厚度和体积的变化,并将其与健康的同龄人进行比较。对于该研究,招募了首次发作时单侧急性AAU的35名患者。在治疗前后,在9个糖尿病视网膜病变早期治疗研究(ETDRS)子区域中,用EDI-OCT测量了小凹下厚度和脉络膜体积。此外,通过光学生物测定法确定两个眼球的轴向长度。在基线时和治疗后的AAU眼睛与另一只眼睛之间,未检测到脉络膜厚度或脉络膜体积的统计学差异。在前,后ETDRS视野以及上外环,均检测到前房耀斑值与绝对CT变化之间的正相关。在基线,治疗后以及同伴眼中,在AAU眼中发现年龄与脉络膜厚度和脉络膜体积两者之间呈负相关。用EDI-OCT评估脉络膜似乎不是监测前葡萄膜炎眼睛的可靠工具。

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