Development of novel electrospun dual-drug fiber mats loaded with a combination of ampicillin and metronidazole

摘要

Objective. Our study was performed with the aim of preparing electrospun polylactide fibers with a combination of ampicillin (AMP) and metronidazole (MNZ) and investigating their drug release behavior and the antibacterial effect on Aggregatibacter actinomycetemcomitans and other oral pathogens.