Apoptosis in alpha interferon (IFN-α) intratumoral chemotherapy for cystic craniopharyngiomas

D. F. Ierardi; M. J. S. Fernandes; I. R. Silva; J. Thomazini-Gouveia; N. S. Silva; P. Dastoli; S. R. C. Toledo; S. Cavalheiro

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Apoptosis in alpha interferon (IFN-α) intratumoral chemotherapy for cystic craniopharyngiomas

机译：α-干扰素（IFN-α）肿瘤内化疗对囊性颅咽管瘤的凋亡

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摘要

The aim of this study was to verify whether intracystic injections of alpha-Interferon (IFN-α) in cystic craniopharyngiomas were able to reduce the tumor by activating the Fas apoptotic pathway.

机译：这项研究的目的是验证在囊性颅咽神经瘤的囊内注射α-干扰素（IFN-α）是否能够通过激活Fas凋亡途径来减轻肿瘤。

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来源
《Child's Nervous System》 |2007年第9期|1041-1046|共6页
作者
D. F. Ierardi; M. J. S. Fernandes; I. R. Silva; J. Thomazini-Gouveia; N. S. Silva; P. Dastoli; S. R. C. Toledo; S. Cavalheiro;
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作者单位

Department of Neurology and NeurosurgeryPediatric Oncology Institute Federal University of São Paulo Rua Botucatu 743 8° andar 04023-062 São Paulo SP Brazil;

Department of Neurology and Neurosurgery Federal University of São PauloEpilepsy Neurobiology Laboratory Rua Pedro de Toledo 781 6° andar 04039-032 São Paulo SP Brazil;

Department of Neurology and Neurosurgery Federal University of São PauloEpilepsy Neurobiology Laboratory Rua Pedro de Toledo 781 6° andar 04039-032 São Paulo SP Brazil;

Pediatric Oncology Institute Federal University of São Paulo Rua Botucatu 743 8° andar 04023-062 São Paulo SP Brazil;

Department of Pediatrics Pediatric Oncology Institute Federal University of São Paulo Rua Botucatu 743 8° andar 04023-062 São Paulo SP Brazil;

Department of Neurology and NeurosurgeryPediatric Oncology Institute Federal University of São Paulo Rua Botucatu 743 8° andar 04023-062 São Paulo SP Brazil;

Department of Genetics Pediatric Oncology Institute Federal University of São Paulo Rua Botucatu 743 8° andar 04023-062 São Paulo SP Brazil;

Department of Neurology and Neurosurgery Pediatric Oncology Institute Federal University of São Paulo Rua Botucatu 591/42 04023-062 São Paulo SP Brazil;

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正文语种 eng
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关键词
Cystic craniopharyngioma; Alpha interferon; Apoptosis; Fas/FasL pathway; Intratumoral chemotherapy; Cell death pathways; Ommaya reservoir;

机译：囊性颅咽管瘤;α干扰素;凋亡;Fas / FasL途径;肿瘤内化学疗法;细胞死亡途径;Ommaya水库;

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专利

1. Apoptosis in alpha interferon (IFN-alpha) intratumoral chemotherapy for cystic craniopharyngiomas. [J] . Ierardi DF, Fernandes MJ, Silva IR, Child's nervous system: ChNS : official journal of the International Society for Pediatric Neurosurgery . 2007,第9期

机译：α干扰素（IFN-α）肿瘤内化疗对囊性颅咽管瘤的凋亡作用。
2. Cystic craniopharyngioma: intratumoral chemotherapy with alpha interferon [J] . Andrea Maria Capellano, Daniela Ierardi, Jardel Mendon?a Nicácio, Arquivos de Neuro-Psiquiatria . 2011,第1期

机译：囊性颅咽管瘤：肿瘤内化疗与α干扰素
3. Use of interferon alpha in intratumoral chemotherapy for cystic craniopharyngioma. [J] . Cavalheiro S, Dastoli PA, Silva NS, Child's nervous system: ChNS : official journal of the International Society for Pediatric Neurosurgery . 2005,第8a9期

机译：干扰素α在囊性颅咽管瘤肿瘤内化疗中的应用。
4. Liposomal lactoferrin induced significant increase of the interferon-alpha (IFN-α) producibility in healthy volunteers [C] . Atsushi Ishikado, Hiromichi Imanaka, Mayumi Kotani, International Conference on Food Factors . 2004

机译：脂质体乳铁蛋白诱导健康志愿者的干扰素-α（IFN-α）的显着增加
5. Intratumoral chemotherapy for liver cancer using biodegradable polymer implants. [D] . Weinberg, Brent Derek. 2007

机译：使用可生物降解的聚合物植入物进行肝癌的肿瘤内化疗。
6. CRAN-35. CHILDHOOD CYSTIC CRANIOPHARYNGIOMA: 15 YEARS OF INTRA-TUMORAL CHEMOTHERAPY WITH INTERFERON-ALPHA AT IOP/GRAACC/UNIFESP [O] . Patricia Dastoli, Jardel Nicácio, Marcos Costa, 2018

机译：CRAN-35。儿童囊性颅咽喉癌：IOP / GRAACC / UNIFESP进行干扰素-α的腔内化学疗法15年
7. Cystic craniopharyngioma: intratumoral chemotherapy with alpha interferon Craniofaringioma cístico: quimioterapia intratumoral com interferon alfa [O] . Patrícia Alessandra Dastoli, Jardel Mendonça Nicácio, Nasjla Saba Silva, 2011

机译：囊性颅咽管瘤：α干扰素在肿瘤内进行化疗颅faringioma癌：quimioterapia肿瘤内com干扰素阿尔法

Apoptosis in alpha interferon (IFN-α) intratumoral chemotherapy for cystic craniopharyngiomas

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