Photoinitiated Polymerisation Of Monolithic Stationary Phases In Polyimide Coated Capillaries Using Visible Region Leds

摘要

The spatially controlled synthesis of poly(glycidyl methacrylate-co-ethylene dimethacrylate) monolithic stationary phases in polyimide coated fused silica capillaries by visible light induced radical polymerisation using a three-component initiator and a 660 nm light emitting diode (LED) as a light source is presented here.rnSince the synthesis of the first organic monolith was reported by Svec and Frechet in 1992, monolithic stationary phases have been recognised as one of most innovative developments since the conception of chromatography by Tsvet in the early 1900s. Initiation by heat and ultraviolet (UV) radiation are the most common methods of inducing polymerisation, while other methods such as initiation by microwaves, γ-radiation and electron beam have been reported more recently. Photo-initiation is of particular interest as it is an excellent method of achieving sharp plugs of monolith in a specific location within a mold in a short amount of time.