Controlled Self-assembly Of Nucleotide-lanthanide Complexes: Specific Formation Of Nanofibers From Dimeric Guanine Nucleotides

摘要

Monomeric and dimeric guanine nucleotides monophosphate spontaneously self-assemble into nanoparticles and nanofibers in the presence of lanthanide ions, which reflects differences in the unit coordination structures and their hierarchical assembly.rnThe self-assembly of oligonucleotides is driven by cooperative and multiple non-covalent interactions (hydrogen bonding, hydrophobic, van der Waals, stacking, electrostatic and ion-dipole interactions). Their self-assembling properties render them interesting candidates for the design of nano-to micrometric structures with a broad diversity of morphologies (DNA origami strategy).