Catalytic stereoselective benzylic C-H functionalizations by oxidative C-H activation and organocatalysis

摘要

An organocatalytic stereoselective α-alkylation reaction of aldehydes based on C-H activation is presented. The activation of C-H bonds has attracted much attention in both the academy and industry because of its many potential advantages. It is anticipated that the formation of new C-X bonds (X = C, O, N, S) via activation of C-H bonds will have a great impact in the field of stereoselective synthesis.