5-(Dimethylamino)-N-(4-ethynylphenyl)-1-naphthalenesulfonamide as a novel bifunctional antitumor agent and two-photon induced bio-imaging probe

摘要

A novel compound, (5-(dimethylamino)-N-(4-ethynylphenyl)-l-naphthalenesulfonamide), was prepared and characterized; it shows dual functional roles as an effective antitumor and a two-photon induced bio-imaging agent. Fluorescence optical imaging probes are paving the way for new methods to sense and spot live molecular targets. Since the application of conventional fluorescent probes is limited by the low specificity of the probes, specific recognition properties by the target biomolecules are essential for the development of sensitive fluorescence-based probes.