Dual colored mesoporous silica nanoparticles with pH activable rhodamine-lactam for ratiometric sensing of lysosomal acidityf

Shuqi Wu; Zhu U; Jiahuai Han; Shoufa Han

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Dual colored mesoporous silica nanoparticles with pH activable rhodamine-lactam for ratiometric sensing of lysosomal acidityf

机译：具有pH活化罗丹明-内酰胺的双色介孔二氧化硅纳米颗粒，用于溶酶体酸度的比例传感

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摘要

Alteration of lysosome acidity has been implicated in many biological events ranging from apoptosis to cancer metastasis, etc. Mesoporous silica nanoparticles doped with acid activable rhodamine-lactam and fluorescein isothiocyanate (FITC) were developed for ratiometric sensing of lysosomal pH changes in live cells with flow cytometry.

机译：溶酶体酸度的改变已牵涉到从凋亡到癌症转移等许多生物学事件中。开发了掺有酸可活化罗丹明-内酰胺和异硫氰酸荧光素（FITC）的中孔二氧化硅纳米颗粒，用于按比例感测流动的活细胞中的溶酶体pH变化。细胞计数。

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《Chemical Communications》 |2011年第40期|p.11276-11278|共3页
作者
Shuqi Wu; Zhu U; Jiahuai Han; Shoufa Han;
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作者单位

Department of Chemical Biology, College of Chemistry and Chemical Engineering, and the Key Laboratory for Chemical Biology of Fujian Province, Xiamen University, Xiamen, Fujian 361005,China;

Department of Chemical Biology, College of Chemistry and Chemical Engineering, and the Key Laboratory for Chemical Biology of Fujian Province, Xiamen University, Xiamen, Fujian 361005,China, State Key Laboratory of Cellular Stress Biology and School of Life Sciences, Xiamen University, Xiamen, Fujian 361005, China;

State Key Laboratory of Cellular Stress Biology and School of Life Sciences, Xiamen University, Xiamen, Fujian 361005, China;

Department of Chemical Biology, College of Chemistry and Chemical Engineering, and the Key Laboratory for Chemical Biology of Fujian Province, Xiamen University, Xiamen, Fujian 361005,China;

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1. Conjugated polymer and spirolactam rhodamine-B derivative co-functionalized mesoporous silica nanoparticles as the scaffold for the FRET-based ratiometric sensing of mercury (II) ions [J] . Feng Lijuan, Sha Jie, He Yao, Microporous and mesoporous materials: The offical journal of the International Zeolite Association . 2015,第Null期

机译：共轭聚合物和螺内酰胺若丹明-B衍生物共官能化的介孔二氧化硅纳米粒子，作为基于FRET的汞（II）离子比例传感的支架
2. Design and fabrication of fluorescence resonance energy transfer-mediated fluorescent polymer nanoparticles for ratiometric sensing of lysosomal pH [J] . Chen Jian, Tang Ying, Wang Hong, Journal of Colloid and Interface Science . 2016,第Null期

机译：用于溶酶体pH的比例传感的荧光共振能量转移介导的荧光聚合物纳米粒子的设计与制备
3. Fluorescent mesoporous silica nanoparticles functionalized graphene oxide: A facile FRET-based ratiometric probe for Hg~(2+) [J] . Haixia Zhang, Cuiyan Tong, Jie Sha, Sensors and Actuators . 2015,第jana期

机译：荧光介孔二氧化硅纳米粒子功能化的氧化石墨烯：Hg〜（2+）的基于FRET的简便比例探针
4. Inclusion of water insoluble active molecules in mesoporous silica nanoparticles [C] . A. Walunj, D. Muzumdar, Y. Inamdar, Annual meeting exposition of the Controlled Release Society . 2009

机译：水不溶性活性分子包含在介孔二氧化硅纳米粒子中
5. Synthesis, characterization, and application of monosized mesoporous silica nanoparticle-supported lipid bilayers for targeted therapeutic delivery to individual cells. [D] . Durfee, Paul Nicholas. 2016

机译：单一尺寸介孔二氧化硅纳米颗粒支持的脂质双层的合成，表征和应用，用于靶向治疗性递送至单个细胞。
6. Involvement of Lysosomal Exocytosis in the Excretion of Mesoporous Silica Nanoparticles and Enhancement of Drug Delivery Effect by Exocytosis Inhibition [O] . Rolando E. Yanes, Derrick Tarn, Angela A. Hwang, -1

机译：溶酶体外尿量参与缺血性二氧化硅纳米粒细胞排泄的排泄胞尿精抑制的增强药物输送效果
7. Dual colored mesoporous silica nanoparticles with pH activable rhodamine-lactam for ratiometric sensing of lysosomal acidity [O] . Wu Shuqi, Li Zhu, Han Jiahuai, 2011

机译：具有pH活化若丹明-内酰胺的双色介孔二氧化硅纳米颗粒，用于溶酶体酸度的比例检测

Dual colored mesoporous silica nanoparticles with pH activable rhodamine-lactam for ratiometric sensing of lysosomal acidityf

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