Preparation of unsymmetrical distyryl BODIPY derivatives and effects of the styryl substituents on their in vitro photodynamic properties

摘要

A series of unsymmetrical distyryl BODIPYs have been prepared which function as highly potent photosensitisers with in vitro IC_50 values as low as 15 nM. Their cellular uptake, subcellular localisation and photocytotoxicity depend greatly on the styryl substituents.