Palladium-catalysed aerobic oxidative Heck-type alkenylation of Csp~3-H for pyrrole synthesis

摘要

The first palladium-catalysed aerobic oxidative intramolecular alkenylation of Csp~3-H bonds was described. The reaction conditions were mild and molecular oxygen was used as the terminal oxidant Kinetic studies showed that the Csp~3-H metallation step was a slow step.