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首页> 外文期刊>Chemical Communications >A ratiometric naphthalimide sensor for live cell imaging of copper(Ⅰ)
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A ratiometric naphthalimide sensor for live cell imaging of copper(Ⅰ)

机译：用于铜活细胞成像的比例式萘二甲酰亚胺传感器（Ⅰ）

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摘要

A new naphthalimide derivative bearing a tetrathia-azacrown for high affinity and selective binding to Cu~+ was synthesised. Copper recognition properties in solution were evaluated using ~1H NMR and fluorescence spectroscopy. Live cell imaging by confocal microscopy highlighted the capabilities of the new sensor for the two-wavelength detection of intracellular monovalent copper in neuronal cells.
机译：合成了一种新的萘四甲酰亚胺衍生物，该衍生物带有四硫杂氮杂卓素，具有很高的亲和力和对Cu〜+的选择性结合。使用〜1H NMR和荧光光谱法评估溶液中的铜识别性能。通过共聚焦显微镜对活细胞进行成像，突显了这种新型传感器在神经元细胞中两波长检测细胞内单价铜的功能。

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  • 来源
    《Chemical Communications》 |2013年第49期|5565-5567|共3页
  • 作者

    Cristina Satriano; Giuseppe Trusso Sfrazzetto; Maria Emanuela Amato; Francesco P. Ballistreri; Agata Copani; Maria Laura Giuffrida; Giuseppe Grasso; Andrea Pappalardo; Enrico Rizzarelli; Gaetano A. Tomaselli; Rosa Maria Toscano;

  • 作者单位

    Department of Chemical Sciences, University of Catania, viale Andrea Doria, 6,95125 Catania, Italy;

    Department of Chemical Sciences, University of Catania, viale Andrea Doria, 6,95125 Catania, Italy;

    Department of Chemical Sciences, University of Catania, viale Andrea Doria, 6,95125 Catania, Italy;

    Department of Chemical Sciences, University of Catania, viale Andrea Doria, 6,95125 Catania, Italy;

    Department of Drug Sciences, University of Catania, Viale Andrea Doria,Catania 95125, Italy,Institute of Biostructure and Bioimaging, National Research Council,Viale Andrea Doria, Catania 95125, Italy;

    Institute of Biostructure and Bioimaging, National Research Council,Viale Andrea Doria, Catania 95125, Italy;

    Department of Chemical Sciences, University of Catania, viale Andrea Doria, 6,95125 Catania, Italy;

    Department of Chemical Sciences, University of Catania, viale Andrea Doria, 6,95125 Catania, Italy;

    Department of Chemical Sciences, University of Catania, viale Andrea Doria, 6,95125 Catania, Italy;

    Department of Chemical Sciences, University of Catania, viale Andrea Doria, 6,95125 Catania, Italy;

    Department of Chemical Sciences, University of Catania, viale Andrea Doria, 6,95125 Catania, Italy;

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