Diastereoselective allylation and crotylation of N-tert-butanesulfinyl imines with allylic alcohols

摘要

The palladium-catalyzed allylation of N-tert-butanesulfinyl imines with allylic alcohols in the presence of Inl as reducing reagent takes place with high diastereoselectivity in reasonable yields. The reaction with crotyl alcohol is totally regioselective, leading to the anti-diastereomer as the main reaction product.