Microarrays of heparin oligosaccharides obtained by nitrous acid depolymerization of isolated heparin

de Paz JL; Spillmann D; Seeberger PH

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Microarrays of heparin oligosaccharides obtained by nitrous acid depolymerization of isolated heparin

机译：亚硝酸对分离的肝素解聚得到的肝素寡糖的微阵列

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摘要

Heparin oligosaccharides derived by nitrous acid depolymerization of heparin have been immobilized on amine-coated glass slides. The formation of a Schiff base creates heparin chips that are a suitable platform for the high-throughput analysis of carbohydrate - protein interactions.

机译：通过亚硝酸肝素解聚得到的肝素寡糖已被固定在涂有胺的载玻片上。 Schiff碱的形成产生了肝素芯片，该芯片是用于高通量分析碳水化合物-蛋白质相互作用的合适平台。

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来源
《Chemical Communications》 |2006年第29期|p. 3116-3118|共3页
作者
de Paz JL; Spillmann D; Seeberger PH;
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作者单位

ETH, Swiss Fed Inst Technol, Organ Chem Lab, CH-8093 Zurich, Switzerland;

Uppsala Univ, Dept Med Biochem & Microbiol, SE-75123 Uppsala, Sweden;

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原文格式 PDF
正文语种 eng
中图分类化学;
关键词
CARBOHYDRATE MICROARRAYS; SULFATE; GLYCOMICS; ARRAYS;

机译：碳水化合物微阵列;硫酸盐;糖类;阵列;

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专利

1. Preparation and use of microarrays containing synthetic heparin oligosaccharides for the rapid analysis of heparin-protein interactions [J] . Noti C, de Paz JL, Polito L, Chemistry: A European journal . 2006,第34期

机译：含有合成肝素寡糖的微阵列的制备和应用，用于肝素-蛋白质相互作用的快速分析
2. Detection of oligosaccharide ligands for Hepatocyte growth factor/Scatter factor (HGF/SF), Keratinocyte growth factor (KGF/FGF-7), RANTES and Heparin cofactor II by neoglycolipid microarrays of glycosaminoglycan-derived oligosaccharide fragments [J] . Yamaguchi K, Tamaki H, Fukui S Glycoconjugate journal . 2006,第7a8期

机译：糖胺聚糖衍生的寡糖片段的新糖脂微阵列检测肝细胞生长因子/分散因子（HGF / SF），角质形成细胞生长因子（KGF / FGF-7），RANTES和肝素辅因子II的寡糖配体
3. Oligosaccharides mapping of nitrous acid degraded heparin through UHPLC-HILIC/WAX-MS [J] . Zhang Tianji, Xie Shaoshuai, Wang Zhangjie, Carbohydrate Polymers: Scientific and Technological Aspects of Industrially Important Polysaccharides . 2020,第期

机译：通过UHPLC-HILIC / WAX-MS将亚硝酸降解肝素的寡糖映射
4. HUMORAL RESPONSE AGAINST MYCOBACTERIAL HEPARIN-BINDING HEMAGGLUTININ: THE ROLE OF METHYLATION STUDIED USING PEPTIDE MICROARRAYS [C] . Remi Desmet, Eric Desmet, Herve Drobecq the European Peptide Symposium . 2007

机译：对肝素结合血凝素的体液反应：使用肽微阵列研究甲基化的作用
5. Aryl amides of uronic acid containing oligosaccharides as bind and block antagonists of heparin-binding proteins [D] . Hattan, Christopher M. 2008

机译：含低聚糖的糖醛酸的芳基酰胺，作为肝素结合蛋白的结合和阻断拮抗剂
6. Towards the assembly of heparin and heparan sulfate oligosaccharide libraries: efficient synthesis of uronic acid and disaccharide building blocks [O] . Akihiro Saito, Masahiro Wakao, Hiroshi Deguchi, -1

机译：朝向肝素和硫酸普乙肝素寡糖文库的组装：有效合成尿酸和二糖构造块
7. Cover Picture: Preparation and Use of Microarrays Containing Synthetic Heparin Oligosaccharides for the Rapid Analysis of Heparin–Protein Interactions (Chem. Eur. J. 34/2006) [O] . Christian Noti, Jose L. de Paz, Laura Polito, 2006

机译：封面图片：制备和使用含有合成肝素寡糖的微阵列，用于快速分析肝素 - 蛋白质相互作用（Chem。欧元。J. 34/2006）
8. THE EFFECT OF HEPARIN ON THE CONCENTRATIONS OF TRIGLYCERIDES AND FREE FATTY ACIDS IN LYMPH [R] . Wei Young, Norman K. Freeman 1955

机译：肝素对淋巴液中甘油三酯和游离脂肪酸浓度的影响

Microarrays of heparin oligosaccharides obtained by nitrous acid depolymerization of isolated heparin

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