Nanoparticle PCR: A New Approach of DNA Amplification

摘要

The polymerase chain reaction (PCR) is a technique for quickly "cloning" a particular piece of DNA in the test tube (rather than in living cells like E. coli). Thanks to this procedure, one can make virtually unlimited copies of a single DNA molecule even though it is initially present in a mixture containing many different DNA molecules. In cooperation with researchers from Shanghai Jiao Tong University, CAS scientists have come up with a novel approach to improve the specificity of PCR. Their work has been published recently online by Angew. Chem. Int. Ed, a world-renowned German journal of applied chemistry.