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首页> 外文期刊>World Journal of Gastroenterology >Expression of vascular endothelial growth factor and its role in oncogenesis of human gastric carcinoma
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Expression of vascular endothelial growth factor and its role in oncogenesis of human gastric carcinoma

机译:血管内皮生长因子的表达及其在人胃癌发生中的作用

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摘要

AIM To establish the role of vascular endothelial growth factor (VEGF) in the oncogenesis. Of human gastric carcinoma more directly. METHODS The expression of VEGF and its receptor Kinase-domain insert containing receptor 9KDR) in human Gastric cancer tissue were observed by Immunohistochemical staining. VEGF levels were Manipulated in human gastric cancer cell using eukaryotic Expression constructs designed to express the complete VEGF_165 complimentary DNA in either the sense or Antisense orientation.
机译:目的建立血管内皮生长因子(VEGF)在肿瘤发生中的作用。人胃癌更直接。方法采用免疫组织化学方法观察人胃癌组织中VEGF及其受体9KDR受体激酶结构域插入片段的表达。使用被设计为以有义或反义方向表达完整的VEGF_165互补DNA的真核表达构建体来操纵人胃癌细胞中的VEGF水平。

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