The effects of vitamin E succinate on the expression of c-jun gene and protein in human gastric cancer SGC-7901 cells

摘要

CONCLUSION: The levels of c-jun mRNA and protein in VES-treated SGC-7901 cells were increased in a dose- and time-dependent manner; the expression of c-jun was prolonged by VES, indicating that c-jun is involved in VES- induced apoptosis in SGC-7901 cells. AIM: To investigate the effects of vitamin E succinate (VES) on the expression of c-jun gene and protein in human gastric cancer SGC-7901 cells. METHODS: After SGC-7901 cells were treated with VES at different doses (5,10,20 mg·L~(-1)) at different time, reverse transcription-PCR technique was used to detect the level of c-jun mRNA; Western Blot was applied to measure the expression of c-jun protein.