Nuclear factor kB activity in patients with acute severe cholangitis

摘要

Conclusion: NF-kB activity in PBMC in patients with ACST increases markedly and the degree of NF-kB activation is correlated with severity of biliary tract infection and clinical outcome. Aim: To determine the NF-kB activity in peripheral blood Mononuclear cells(PNMC)in patients with acute cholangitis Of severe type(ACST)and correlate the degree of NF-kB Activation with severity of biliary infection and clinical Outcome. Methods: Twenty patients with ACST were divided into Survivor group(13 cases)and nonsurvivor group(7 cases). Other ten patients undergoing elective gastrectomy or Inguinal hernia repair were selected as control group.