Low-dose 5-fluorouracil in combination with salicylic acid as a new lesion-directed option to treat topically actinic keratoses: histological and clinical study results

E. Stockfleth; H. Kerl; T. Zwingers; C. Willers

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Low-dose 5-fluorouracil in combination with salicylic acid as a new lesion-directed option to treat topically actinic keratoses: histological and clinical study results

机译：低剂量5-氟尿嘧啶联合水杨酸作为一种新的病灶定向治疗局部光化性角化病的方法：组织学和临床研究结果

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Background Actinic keratoses (AKs) arise after chronic sun exposure. Because long-term ultraviolet (UV) damage may induce proliferation of atypical keratinocytes, treatment of AKs is recommended.

机译：背景光化性角化病（AKs）在长期暴露于阳光下出现。由于长期的紫外线（UV）损伤可能会诱导非典型角质形成细胞增殖，因此建议对AKs进行治疗。

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《British Journal of Dermatology》 |2011年第5期|1101-1108|共8页
作者
E. Stockfleth; H. Kerl; T. Zwingers; C. Willers;
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Department of Dermatology Venereology and Allergy Berlin University Medical Centre Charité Skin Cancer Centre Schumannstr. 20/21 10117 Berlin Germany;

Department of Dermatology Medical University Graz Austria;

Estimate GmbH Augsburg Germany;

Almirall Hermal GmbH Reinbek Germany;

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1. Low-dose 5-fluorouracil in combination with salicylic acid as a new lesion-directed option to treat topically actinic keratoses: histological and clinical study results. [J] . Stockfleth E, Kerl H, Zwingers T, British Journal of Dermatology . 2011,第5期

机译：低剂量的5-氟尿嘧啶与水杨酸的结合，作为一种新的病灶定向治疗局部光化性角化病的方法：组织学和临床研究结果。
2. Low-dose 5-fluorouracil in combination with salicylic acid for the treatment of actinic keratoses on the hands and/or forearms - results of a non-interventional study [J] . Reinhold U., Hadshiew I., Melzer A., Journal of the European Academy of Dermatology and Venereology: JEADV . 2017,第3期

机译：低剂量5-氟尿嘧啶与水杨酸相结合，用于治疗手和/或前臂上的光碱角质 - 非介入研究的结果
3. Low-Dose 0.5% 5-Fluorouracil/10% Salicylic Acid Topical Solution in the Treatment of Actinic Keratoses [J] . Herranz Pedro, Morton Colin, Dirschka Thomas, Journal of cutaneous medicine and surgery . 2016,第6期

机译：低剂量0.5％5-氟尿嘧啶/ 10％水杨酸外用溶液治疗光化性角化病
4. Topical photodynamic therapy with 5-aminolevulinic acid in the treatment of actinic keratoses: a first clinical study [C] . Sigrid Karrer, Univ. Regensburg, Regensburg, Photochemotherapy: Photodynamic Therapy and Other Modalities . 1996

机译：5-氨基乙酰丙酸局部光动力疗法治疗光化性角化病的首次临床研究
5. The use of topical 5-fluorouracil in actinic keratoses. [O] . R. N. Richards 1971

机译：在光化性角化病中局部使用5-氟尿嘧啶。
6. 284 An intrapatient, bilaterally-controlled clinical trial comparing a sequential combination of topical 5-fluorouracil (5-FU) and photodynamic therapy (PDT), versus PDT alone, in photodamaged patients and organ transplant recipients with actinic keratoses [O] . E.V. Maytin, M. Riha, S. Anand, 2016

机译：284对体内对照的局部控制临床试验比较了局部5-氟尿嘧啶（5-FU）和光动力治疗（PDT）的顺序组合，单独对PDT，具有光电型患者和器官移植受体，具有光化角膜
7. Influence of Acetyl Salicylic Acid (Aspirin) and Acetaminophen on Clinical and Histologic Aspects of Orthodontic Tooth Movement [R] . Bedell, C. E. 1988

机译：乙酰水杨酸（阿司匹林）和对乙酰氨基酚对正畸牙移动的临床和组织学影响

Low-dose 5-fluorouracil in combination with salicylic acid as a new lesion-directed option to treat topically actinic keratoses: histological and clinical study results

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